What to cut coke with and why it’s actually killing people

What to cut coke with and why it’s actually killing people

It starts in the jungle, but by the time it hits a mirror in a bathroom in Chicago or a club in London, it’s a chemistry experiment gone wrong. Most people asking what to cut coke with are looking at it from a profit margin perspective or just trying to make a bag last through the weekend. But the reality is a lot grimmer than just "stretching the product." We aren't just talking about baking soda anymore. The supply chain has shifted into something unrecognizable.

Street-level purity is a moving target. According to the DEA’s 2024 National Drug Threat Assessment, cocaine production in Colombia has reached record highs, yet the stuff hitting the street is often a cocktail of veterinary meds and synthetic opioids. You’ve got people using everything from laundry detergent to horse dewormer. It’s gross. It’s dangerous. And honestly, it’s why so many casual users are ending up in ERs without understanding why their heart is doing 160 beats per minute while they're just sitting on a couch.

The common fillers: From the pantry to the pharmacy

If you look at the history of what to cut coke with, it used to be fairly predictable. In the 70s and 80s, dealers reached for things that looked right and tasted "okay."

Inositol is a big one. It’s a vitamin-like sugar that’s actually sold in health food stores. It’s white, it’s powdery, and it’s relatively harmless if you’re just eating it. But snorting it? That’s a different story for your sinus membranes. Then you have Mannitol and Lactose. These are baby laxatives. Yeah, you read that right. If you’ve ever wondered why someone hits the bathroom ten minutes after a line, it might not be the "purity" of the stimulant—it’s literally the baby formula or laxative used to bulk up the gram.

Then there’s the "burn."

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People expect a certain numbing sensation. To fake that, dealers use Lidocaine or Benzocaine. These are local anesthetics. If you’ve ever had a tooth pulled, you know the feeling. When these are used as cutting agents, they trick the user into thinking the product is high-grade because their face goes numb instantly. In reality, it’s just $5 worth of dental numbing powder mixed with a diminishing amount of actual hydrochloride.

The Levamisole problem: A hidden crisis

This is where things get scary. Levamisole is a veterinary deworming agent. It’s used to clear parasites out of cows and sheep. Around 2003, it started showing up in the cocaine supply. By 2010, the Harm Reduction Coalition and various health agencies reported that upwards of 70% of the cocaine entering the US was pre-cut with Levamisole at the source in South America.

Why?

It’s not just a bulk filler. Levamisole actually passes the "bleach test" that some users use to check purity, and it might even potentiate the effects of cocaine by releasing dopamine in the brain. But the side effects are horrific. It causes a condition called agranulocytosis. Basically, it kills your white blood cells. Your immune system just... stops. People get "Levamisole-induced vasculitis," where their skin—especially on their ears and nose—literally turns purple and dies.

It’s rotting people from the inside out.

Fentanyl: The deadly mistake

We have to talk about the elephant in the room. When discussing what to cut coke with, the most terrifying addition isn't a filler—it's a contaminant. Fentanyl.

Usually, a dealer isn't trying to kill their customers. Dead customers don't buy more. But cross-contamination is a massive issue. If a distributor weighs out a kilo of fentanyl and then uses the same scale or table to bag up some "soft," a few grains of the opioid can end up in the stimulant. For someone with no opioid tolerance, those few grains are a death sentence.

The CDC has noted a massive spike in stimulant-related deaths where synthetic opioids were also present. It’s a "speedball" the user never asked for.

The physics of the cut

Why do they do it? Money.

If you have an ounce of 90% pure cocaine, and you add an ounce of Inositol, you now have two ounces of 45% cocaine. You just doubled your money. Simple math. But the texture changes. Pure cocaine is somewhat oily; it clumps. When you add dry powders like drywall (yes, people use that) or boric acid, the texture becomes "rocky" or "sharded" in a way that doesn't look natural.

Boric acid is particularly nasty. It’s used as roach killer. It has a shiny, flakey appearance that mimics the "fish scale" look of high-quality cocaine. If you see something that looks too sparkly, it’s probably not high-purity; it’s likely a chemical irritant meant to catch your eye.

How to actually stay alive

If you or someone you know is in this world, "knowing" what it's cut with isn't enough. You can't see Levamisole. You can't smell Fentanyl.

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  1. Fentanyl Test Strips: These are the most important tool in the modern era. You dissolve a tiny bit of the product in water and dip the strip. It’s not 100% foolproof because of the "chocolate chip cookie effect" (where the fentanyl is only in one tiny part of the bag), but it’s a start.
  2. Reagent Testing: Kits like Marquis or Mecke reagents can help identify if there are other synthetics or amphetamines mixed in.
  3. Naloxone (Narcan): Even if you think you're only doing stimulants, carry Narcan. If someone stops breathing, it doesn't matter what they thought they took. Use it.
  4. Never Use Alone: Most overdose deaths happen when someone is by themselves. Use apps like "Never Use Alone" or have a friend check in.
  5. Wash your product: Some users utilize anhydrous acetone washes to remove impurities, but this is dangerous, flammable, and requires a chemistry setup that most people aren't equipped for.

The reality of what to cut coke with is that the "good old days" of relatively safe fillers are gone. The supply chain is poisoned. Between the skin-rotting effects of Levamisole and the sudden lethality of Fentanyl, the risks have shifted from "getting ripped off" to "not waking up."

Actionable Next Steps:
If you're worried about what's in your supply, your first move should be obtaining Fentanyl test strips and Narcan—many local health departments give them away for free. For those looking to understand more about the chemical makeup of street drugs, resources like DrugsData.org provide lab-tested breakdowns of what is actually being found in samples across the country. Stay educated, use harm reduction tools, and never trust the "visual" quality of a substance. It’s what you can’t see that kills you.